If the Jamaican society is to extricate itself from its four decades of economic malaise, the 40-year trend of increasing violent crime and insecurity must be reversed. However, this is only possible with proper and adequate diagnoses of causes and the formulation of appropriate policies and solutions. Jamaica and the rest of the Caribbean must adopt (and adapt) relevant crime response policies and approaches to fight all types of crimes and violence, and the authors argue that this is only achievable through coordinated strategies and evidence-based policymaking underpinned by an integrated program of cutting-edge research. By identifying the best program assessment indicators and adjusting policies that are inadequate, a country like Jamaica can turn the tide against the criminal organizations that are holding the formal economy and legal institutions hostage. Through careful analysis of other regional programs and perspectives, it is possible to find workable models for Jamaica to follow.