As Chinese trade and investment with Latin America expand, the People's Republic of China (PRC) is accumulating interests in the region. Whatever Chinese intentions toward Latin America may be, the dilemma of when and how to defend these interests is likely to occupy a significant part of the PRC agenda in the region in the coming decades, and to affect China's relationship with the United States as well. This article identifies six emerging Chinese interests in Latin America, and discusses why, and how the PRC may struggle to defend them. These interests are: (1) Access to markets and the fight against protectionism, (2) Protection of investments and contracts, (3) Repayment of loans, (4) Protection of resource flows, (5) Protection of Chinese nationals and operations in the region, and the (6) Isolation of Taiwan.