The article analyzes interdependency levels in security affairs, pointing out that the best accomplishments have been carried out in South America, such as multinational cooperation in the UN mission in Haiti. It is also pointed out that, regarding security and defense in North America, there are plenty of obstacles meant to be overcome by means of implementing the Merida Initiative for México and Central America. In the case of Andean countries-at present, the most conflictive region in the hemisphere-actual steps backwards have occurred, increasing geopolitical and border tensions among its members. The paper concludes that at present, the paradigm between security and integration must not be mutually exclusive. It faces growing challenges which demand the creation of institutions that are able to deal with them.